3-((2-(Acetoxymethyl)-3-methylpyridin-4-yl)oxy)propyl Acetate




3-((2-(Acetoxymethyl)-3-methylpyridin-4-yl)oxy)propyl Acetate


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Catalogue NumberA167225
Chemical Name3-((2-(Acetoxymethyl)-3-methylpyridin-4-yl)oxy)propyl Acetate
Synonyms4-[3-(Acetyloxy)propoxy]-3-methyl-2-pyridinemethanol 2-Acetate
CAS Number675818-43-6
Molecular FormulaC₁₄H₁₉NO₅
Molecular Weight281.3
Category Building Blocks; Miscellaneous;
Applications3-((2-(Acetoxymethyl)-3-methylpyridin-4-yl)oxy)propyl Acetate is an intermediate in the synthesis of 2-(Chloromethyl)-4-(3-chloropropoxy)-3-methylpyridine Hydrochloride (C369080), an impurity of Rabeprazole (R070540). Rabeprazole is a partially reversible gastric proton pump inhibitor.
ReferencesMorii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993); Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994); Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

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