Abamine




Abamine


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Catalogue NumberA107200
Chemical NameAbamine
SynonymsN-[(2E)-3-(3,4-Dimethoxyphenyl)-2-propen-1-yl]-N-[(4-fluorophenyl)methyl]-glycine Methyl Ester; N-[(2E)-3-(3,4-Dimethoxyphenyl)-2-propenyl]-N-[(4-fluorophenyl)methyl]-glycine Methyl Ester
CAS Number729612-64-0
Molecular FormulaC₂₁H₂₄FNO₄
AppearanceLight Yellow Oil
Molecular Weight373.42
StorageAmber Vial, Refrigerator, Under inert atmosphere
SolubilityChloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Category Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
ApplicationsAbamine is an inhibitor of 9-Cis-Epoxycarotenoid dioxygenase (NCED), the key regulatory enzyme in the plant hormone abscisic acid (ABA) biosynthesis pathway.
ReferencesKitahata, N., et al.: Bioorg. Med. Chem., 14, 5555 (2006); Han, S., et al.: Bioorg. Med. Chem. Lett., 14, 3033 (2004)

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